Cagrilintide

Cagrilintide is a long-acting amylin analogue developed for research into appetite regulation and weight management, particularly in combination with GLP receptor agonists. As a modified form of human amylin, Cagrilintide has demonstrated promising effects in delaying gastric emptying, increasing satiety, and reducing caloric intake in preclinical models.

Its mechanism of action complements GLP-1 analogues, making it a popular compound in dual-agonist research. Investigators have studied Cagrilintide for its ability to improve metabolic markers, regulate energy balance, and support sustained weight loss effects in rodent and non-human primate models.